(MCD, holocarboxylase synthetase) Multiple carboxylase deficiency

A deficiency of biotin, part of the Vitamin B complex, leading to multiple carboxylase deficiency. Incidence is 1 in 87,000. Symptoms include seizures, hypotonia, immune system impairment, skin rashes, hair loss, hearing loss and mental retardation. Treatment is oral biotin supplementation, which should be begun immediately upon diagnosis.

Does HCSD go by any other names?
Also known as: HCSD (HOLOCARBOXYLASE SYNTHETASE DEFICIENCY)​ Holocarboxylase deficiency, HLCS deficiency, Multiple carboxylase deficiency, early-onset infant multiple carboxylase deficiency, MCD, neonatal form early onset combined carboxylase deficiency,